TÜBİTAK 1001 project titled “Observation of Autograft Formation and Comprehensive Analysis of the Preclinical Process through Long-Term Implantation of Double-Layered Small-Caliber Vascular Grafts Produced from Biodegradable Polymeric Fibers into the Porcine Carotid Artery,” conducted under the leadership of our faculty member Assoc. Prof. Dr. İpek Yalçın Eniş, has been successfully completed.

Within the scope of the project, double-layered vascular grafts developed using the electrospinning method were designed to mimic the mechanical and biological properties of the target artery. Their mechanical performance, biocompatibility, and patency were successfully validated through in vivo studies carried out on a large animal model.

Throughout the project, 5 graduate students, 2 undergraduate students, 5 STAR scholars, and 1 GENÇ STAR scholar were supported. The scientific outcomes obtained were transformed into numerous international publications and formed the basis for new research projects (e.g., TÜSEB 2025-B-01; 46602). The project has made significant contributions to our country’s scientific and technological research capacity, the training of qualified researchers, and the strengthening of the research ecosystem.

At the same time, the study provides a strong R&D infrastructure that can enhance Türkiye’s competitiveness in the global market for biodegradable vascular grafts, which is expected to take shape in the near future.

We congratulate Assoc. Prof. Dr. İpek Yalçın Eniş, Assoc. Prof. Dr. Hande Sezgin, Research Assistant Janset Öztemur Sezgin, Research Assistant Suzan Özdemir, and the entire project team who contributed through interdisciplinary collaboration, and we wish them continued success.