Tubitak 1001 Projects 2021 I. Term application results were announced on 8 July 2021. 247 of the 2233 projects that were evaluated, were accepted. 12 of the supported projects are coordinated by Istanbul Technical University faculty members, and 2 of these projects belong to our faculty members Assoc. Prof. Dr. Alper Gürarslan and Assis. Prof. Dr. İpek Yalçın Eniş.
Project name: Sustainable Electronic, Protective and Medical Textile Applications of Poplar Fibers
Project Coordinator: Assoc. Prof. Dr. Alper GÜRARSLAN
Project Team: In the Project that Assoc. Prof. Dr.Özgür Atalay is involved from our faculty, researchers from Marmara University Textile Engineering Department also take part.
Project Summary: Poplar fibers, a natural material that is not currently used in any product in the project, will be transformed into functional textile products with high added value. For this purpose, electronic textile and medical textile products will be developed from poplar fibers. 3 graduate students will be supported in this project which will last for 3 years.
Project name: Observation of autograft formation with long-term implantation of bilayer small-caliber vascular grafts made of biodegradable polymeric fibers into the porcine carotid artery and a holistic analysis of the pre-clinical process
Project Coordinator: Assis. Prof. Dr. İpek YALÇIN ENİŞ
Project Team: In the project in which Lecturer Dr. Hande Sezgin, Res. Assis. Janset Öztemur and Res. Assis. Suzan Özdemir involved from our faculty, researchers from Bursa Uludağ University Faculty of Medicine and Bursa Uludağ University Faculty of Veterinary Medicine are also involved.
Project Summary: Within the scope of this project, biodegradable and layered tubular scaffolds containing nano and micro fibers will be produced by electrospinning method and subjected to morphological, physical, instrumental, mechanical and biological tests in the light of determined design criterias. The grafts, whose in-vitro process is successful, will be implanted in the pig carotid artery for 18 months, and the behavior of the grafts in the in-vivo environment will be investigated by imaging techniques. It will be possible to detect the formation of structural proteins in the grafts that are explanted at regular intervals by histological and immunohistochemical staining techniques, to observe the possible calcification formation and to determine the structural changes in the in-vivo environment with subsequent mechanical analyzes; the results obtained will be compared with the native carotid artery of the same pig. The success of long-term implantation of vascular grafts in a large animal model will guide the successful surgical applicability of small-caliber biodegradable vascular grafts against cardiovascular diseases. 6 graduate and 2 undergraduate students will be supported in this project, which will last for 3 years.